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49ers -7.0
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Lions vs. 49ers Best Point Spread 1/28/24

Lions vs. 49ers Best Point Spread 1/28/24

FINAL
31-34
FOX
Levi's Stadium
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Detroit Lions vs. San Francisco 49ers Game Pick

The Detroit Lions take on the San Francisco 49ers at Levi's Stadium on Sunday, January 28th, at 6:30 PM EST

Detroit Lions vs. San Francisco 49ers Odds

Moneyline: Lions +260 (Caesars Casino), 49ers -300 (BetMGM)

Point Spread: Lions +7.0 (-114 BetRivers), 49ers -6.5 (-118 DraftKings)

Total: Over 50.5 (-115 BetMGM), Under 51.0 (-110 PointsBet)

Betting Trends

ATS: Lions: 13-6, 49ers: 9-9

Over/Under: Lions: 10-7, 49ers: 9-8-1

Matchup Preview

In a highly anticipated matchup, the Detroit Lions will take on the San Francisco 49ers. The Lions will rely on quarterback Jared Goff, who had an impressive performance in his last game, completing 22 out of 27 passes for 277 yards and a touchdown. Running back David Montgomery will provide support in the ground game, averaging 4.1 yards per carry and scoring a touchdown. Wide receiver Amon-Ra St. Brown will be a key target for Goff, coming off a 110-yard receiving game. On the other side, the 49ers will look to quarterback Brock Purdy and running back Christian McCaffrey for offensive firepower. Purdy threw for 252 yards and a touchdown in his last outing, while McCaffrey rushed for 98 yards and found the end zone twice. Wide receiver Jauan Jennings will be a reliable target for Purdy, coming off a 61-yard receiving game. Both teams have shown promise early in the season, making this a must-watch game.

Spread pick: 49ers

Lines.com 1/21 4:00 PM
NFL Computer Pick
49ers -7.0
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