The San Francisco 49ers take on the Los Angeles Rams September 22nd, 2024 at SoFi Stadium at 4:25 pm
The San Francisco 49ers will face off against the Los Angeles Rams at SoFi Stadium on Sunday, September 22nd, at 4:25 PM EDT. The 49ers, led by Brock Purdy, have shown solid offensive capabilities with Purdy’s 550 passing yards and Jordan Mason’s strong rushing performance. Despite key injuries to Deebo Samuel Sr. and Christian McCaffrey, the 49ers’ depth and defensive efficiency should help them maintain their competitive edge. The Rams, dealing with significant injuries including Cooper Kupp, will rely heavily on Matthew Stafford and Kyren Williams. However, the Rams’ offensive struggles and defensive inefficiencies make them vulnerable against a well-rounded 49ers team. Expect the 49ers to exploit the Rams’ weaknesses and cover the spread.
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