San Francisco 49ers vs. Kansas City Chiefs Game Pick

The San Francisco 49ers take on the Kansas City Chiefs at Allegiant Stadium on Sunday, February 11th, at 6:30 PM EST

San Francisco 49ers vs. Kansas City Chiefs Odds

Moneyline: 49ers -125 (DraftKings), Chiefs +110 (PointsBet)

Point Spread: 49ers -2.0 (-105 DraftKings), Chiefs +2.5 (-115 FanDuel)

Total: Over 47.5 (-110 PointsBet), Under 47.5 (-108 DraftKings)

Betting Trends

Record: San Francisco 49ers: 2-0 Kansas City Chiefs: 3-0

ATS: San Francisco 49ers: 1-1 Kansas City Chiefs: 2-1

Over/Under: San Francisco 49ers: 1-2 Kansas City Chiefs: 3-0

Matchup Preview

In a highly anticipated matchup, the San Francisco 49ers will face off against the Kansas City Chiefs. The 49ers, led by quarterback Brock Purdy, have shown great efficiency on offense, with Purdy completing 43 of 70 passes for 519 yards and 2 touchdowns. Running back Christian McCaffrey has been a force, rushing for 188 yards and 4 touchdowns. Wide receiver Deebo Samuel has been a reliable target, recording 10 receptions for 113 yards. However, the Chiefs, led by quarterback Patrick Mahomes, have been equally impressive. Mahomes has thrown for 718 yards and 4 touchdowns, while running back Isiah Pacheco has rushed for 254 yards and 3 touchdowns. Tight end Travis Kelce and wide receiver Rashee Rice have been key contributors in the passing game. Both teams have had success this season, with the 49ers boasting a 3-0 record and the Chiefs at 2-0. The 49ers have shown a strong offensive and defensive efficiency, while the Chiefs have been dominant on offense. Despite the 49ers' strong start, the Chiefs' offensive firepower gives them the edge in this matchup. Moneyline pick: Chiefs