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San Francisco 49ers vs. Arizona Cardinals Over/Under 01/05/2025

January 5
16:25
FOX
State Farm Stadium
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San Francisco 49ers vs. Arizona Cardinals GAME PICK

The San Francisco 49ers take on the Arizona Cardinals January 5th, 2025 at State Farm Stadium at 4:25 pm

San Francisco 49ers vs. Arizona Cardinals ODDS

Moneyline: 49ers —, Cardinals — Point Spread: 49ers —, Cardinals — Total: Over —, Under —

BETTING TRENDS

  • Record: 49ers: 7-9 Cardinals: 5-10
  • ATS: 49ers: 6-8 Cardinals: 8-7
  • Over/Under: 49ers: 6-9 Cardinals: 9-5

MATCHUP PREVIEW

The San Francisco 49ers will clash with the Arizona Cardinals at State Farm Stadium on January 5th, 2025, at 4:25 PM. The 49ers are facing a challenging season with a 6-9 record and a slew of injuries to key players like Christian McCaffrey and Trent Williams. Brock Purdy has been solid, but the absence of top offensive weapons might limit their scoring ability. The Cardinals, at 7-9, are slightly better positioned, with Kyler Murray leading the charge. Murray’s dual-threat capabilities and a relatively healthier roster give Arizona an edge. Despite some injury concerns, like James Conner’s questionable status, the Cardinals have shown resilience, particularly with Trey McBride and Marvin Harrison Jr. contributing significantly. Given the 49ers’ depleted lineup and the Cardinals’ ability to exploit defensive gaps, this matchup leans towards a higher scoring affair, especially with the total set at 46.5. Both teams have shown tendencies to go over in recent games, making the over a compelling choice for bettors.

NFL Computer Pick
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Lines.com 12/28 16:29

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